
- Injection, monthly
- From $399/month
- Injection, 2 months
- $750 ($375/month)
- New patients
- $100 off the first month
- Oral capsules
- $399/month

What you get for the price
Your tirzepatide price includes the compounded medication, dispensing by a licensed U.S. pharmacy, and the clinical care that goes with a GLP-1 treatment: an online visit with a licensed clinician, a personalized plan, gradual dose increases, and follow-up to see how you're doing. There's no membership fee.
Shipping and taxes, where they apply, are shown before you pay. Labs are billed separately at listed prices, such as $199 for a Comprehensive Lab Panel, if your clinician needs baseline or follow-up results.
Monthly, 3-month and 6-month options
Monthly billing for the injection starts at $399. If you and your clinician expect you to continue, the 2-month package at $750 ($375 per month) lowers your average monthly cost. New patients get $100 off the first month. The oral capsules are billed monthly at $399.
Many people start month to month while their dose is being stepped up and side effects are settling, then move to a package once they know the medication suits them.
- 12 months, billed monthly: $4,788
- Six 2-month packages: $4,500
- New patients: $100 off the first month
- Each lab panel: $199
Tirzepatide versus semaglutide on price
At HealifyMD, compounded semaglutide injection starts at $299 per month and compounded tirzepatide at $399 per month, a difference of $100 a month or $1,200 a year at monthly billing. The two medicines work differently: semaglutide acts on the GLP-1 receptor, while tirzepatide acts on both GIP and GLP-1 receptors.
In SURMOUNT-5, a 72-week head-to-head trial of the branded products in 751 adults with obesity and without type 2 diabetes, people on tirzepatide lost about 20.2% of body weight on average compared with about 13.7% on semaglutide, with similar rates of nausea. Those results come from branded Zepbound and Wegovy, not compounded products, and individual results vary. Whether the extra cost makes sense for you is a decision to make with your clinician, based on your health, goals and how you respond.
Compounded tirzepatide is not Zepbound
The tirzepatide we prescribe is compounded by a licensed pharmacy. Compounded drugs are not FDA-approved, the FDA does not review them for safety, effectiveness or quality before marketing, and they are not equivalent to or interchangeable with Zepbound or Mounjaro.
The FDA has received adverse event reports involving compounded GLP-1 medicines, including compounded tirzepatide, and has flagged dosing errors as a concern. Your clinician will show you how your medication is supplied and how to measure each dose correctly.
Safety considerations
Tirzepatide's most common side effects are nausea, diarrhea, vomiting, constipation, reduced appetite and indigestion. Branded tirzepatide has a boxed warning about thyroid C-cell tumors in rats, and people with a personal or family history of medullary thyroid carcinoma or MEN 2 are generally told not to use it. Pancreatitis and gallbladder problems are also part of the risk discussion.
Tirzepatide can make birth control pills less effective, so branded labeling advises a backup or non-oral method for 4 weeks after starting and after each dose increase. It is not used during pregnancy.
Budgeting for the long run
Weight-loss medicines tend to work while you take them, and in trials of branded GLP-1 drugs, many people regained weight after stopping. That makes it worth thinking about cost over a year or more, not just the first few months, and about how you'd like to handle maintenance later.
Talk with your clinician about a realistic plan: how long you might stay on the medication, what milestones would prompt a review, and whether a lower-cost option could make sense down the line. Building strength training and adequate protein into your routine also helps protect muscle while you lose weight, which matters more after 40.
- Plan for at least several months before judging results
- Review progress and side effects with your clinician at each step
- Discuss maintenance options before you stop
Insurance, branded options and HSA/FSA
Insurance generally doesn't cover compounded tirzepatide. Coverage for branded Zepbound varies by plan and usually requires prior authorization, and Medicare rules for weight-loss drugs have been changing, so check with your plan. If you get a branded GLP-1 through your own coverage or a manufacturer's self-pay program, our Weight Loss Program Membership (from $75 per month) provides clinical oversight without the medication.
IRS guidance counts weight-loss treatment for a physician-diagnosed disease, and prescribed medicines, as medical expenses. Your plan administrator decides whether your purchase qualifies, so ask before paying.
| Item | Price | Billing |
|---|---|---|
| Tirzepatide Injection (compounded) | From $399/month | Monthly |
| Tirzepatide Injection, 2-month package | $750 ($375/month) | Prepaid package |
| New-patient offer, tirzepatide injection | $100 off | First month |
| Tirzepatide Oral Capsules (compounded) | $399/month | Monthly |
| Semaglutide Injection (compounded), for comparison | From $299/month | Monthly |
| Weight Loss Program Membership (for members on branded GLP-1s) | From $75/month | Monthly, or 3 months for $150 |
| Comprehensive Lab Panel | $199 | One-time per panel |
Common questions
How much is tirzepatide per month?
Compounded tirzepatide injection starts at $399 per month, and the oral capsules are $399 per month. Your exact price is confirmed at your eligibility review.
Is a package worth it?
A package lowers your average monthly cost if you continue for the full period. Many people wait until they know the medication suits them.
Why does tirzepatide cost more than semaglutide?
It's a different molecule with a different cost to prepare. Your clinician can help you decide whether it's the better fit for you.
Is compounded tirzepatide the same as Zepbound?
No. It isn't FDA-approved and isn't interchangeable with Zepbound or Mounjaro.
Are labs included in the price?
No. Labs are billed separately, such as $199 for a Comprehensive Lab Panel.
Does insurance cover it?
Insurance generally doesn't cover compounded tirzepatide. Branded coverage depends on your plan.
Can I pay with an HSA or FSA?
It may qualify if it treats a diagnosed condition. Check with your plan administrator before paying.
Sources
We cite government agencies, professional societies and peer-reviewed research. See our editorial policy.
- FDA's Concerns with Unapproved GLP-1 Drugs Used for Weight LossU.S. Food and Drug Administration
- Tirzepatide InjectionMedlinePlus (U.S. National Library of Medicine)
- Tirzepatide as Compared with Semaglutide for the Treatment of ObesityNew England Journal of Medicine (via PubMed)
- Head-to-Head Trial Compares Weight Loss DrugsWeill Cornell Medicine
- Compounding and the FDA: Questions and AnswersU.S. Food and Drug Administration
- Publication 502: Medical and Dental ExpensesInternal Revenue Service